Reducing the Health and Digital Divides: A Model for Using Community‐Based Participatory Research Approach to E‐Health Interventions in Low‐Income Hispanic Communities

Low‐income Hispanics are the most digitally underserved population in the U.S. This article examines the potential of community‐based participatory research approach to e‐health to decrease the disparities in access to technology and health information in low‐income Hispanic communities. To demonstrate this framework, we describe the process of designing a community‐based e‐health intervention to increase knowledge and parental self‐efficacy in coping with young children's mental health problems including mental health service utilization. Our model incorporates utilizing promotoras de salud (lay community health educators) and community media principles to create the content of e‐health interventions and train community members in using the technology. This case study illustrates the processes involved in using this approach, barriers for participatory e‐health interventions in bridging the Digital Divide, and lessons learned.     

Luminescent Eu(III) hybrid sensors for in situ copper detection

In this work we used the sol-gel technique to develop luminescent Eu(III) transparent films deposited on glass slides to build for sensor devices capable of monitoring transition metal ions in aqueous solutions. The films were obtained from a bis(trialkoxysilyl) organic precursor synthesized from the amide of the 2,6-pyridinedicarboxylic acid (DPA) with aminopropyltriethoxysilane (APTES) in the presence or absence of cetyl trimethyl ammonium bromide (CTAB) surfactant as templating agent and triethylethoxysilane (TEOS) as crosslinker. These sensor devices were used to perform in situ quenching experiments by Cu(II), Fe(III), Co(II) and Ni(II) ions. The results indicate that the templated films allow the detection and quantification of these metals down to ppb levels by means of the values of the Stern-Volmer constants. In particular, it was shown that Cu(II) acts as an extremely efficient quencher (K_SV = 3.5 × 10⁵ M⁻¹) when compared with the results obtained for the other metals, opening the possibility to use these devices as potential Cu(II) sensors for actual applications in aqueous media.     

Multimodal augmented reality tangible gaming

This paper presents tangible augmented reality gaming environment that can be used to enhance entertainment using a multimodal tracking interface. Players can interact using different combinations between a pinch glove, a Wiimote, a six-degrees-of-freedom tracker, through tangible ways as well as through I/O controls. Two tabletop augmented reality games have been designed and implemented including a racing game and a pile game. The goal of the augmented reality racing game is to start the car and move around the track without colliding with either the wall or the objects that exist in the gaming arena. Initial evaluation results showed that multimodal-based interaction games can be beneficial in gaming. Based on these results, an augmented reality pile game was implemented with goal of completing a circuit of pipes (from a starting point to an end point on a grid). Initial evaluation showed that tangible interaction is preferred to keyboard interaction and that tangible games are much more enjoyable.     

The use of ‘exploratory learning’ for supporting immersive learning in virtual environments

User interfaces are becoming more intuitive following the requirements of the individual learner and reinforcing the drive towards more personalised learning and greater learner autonomy. There are clearly a new set of challenges emerging for teaching practitioners that will have implications upon not just what is learned but importantly upon lesson planning. This paper explores these changes to teaching through a consideration of an exploratory learning model which allows practitioners to rethink how they teach in 3D and immersive spaces where learning sequences and experiences are choreographed to support peer interactions and exchanges. The ELM extends from Kolb’s experiential learning model to adapt the use of 3D applications, and provides examples from research and development projects to exemplify how the model works in practice. Teaching in these contexts provides less emphasis upon curriculum and more emphasis upon sequencing learning experiences, meta-reflection, peer assessment and group work.     

Sources and nature of secondary school teachers’ education in computer-related ergonomics

Teachers’ knowledge of computer-related ergonomics in education will have an effect on the learning process and the work practices of their students. However little is known about teacher education in this area. The study aimed to investigate the sources and nature of secondary school teachers’ education about computer-related ergonomics. It also investigated the use of computers by secondary school children. The study included all secondary schools in the Republic of Ireland. The findings suggest that computers are widely available and are used frequently by students and teachers. However, there is evidence that teachers are not receiving information on computer-related ergonomics. Teachers were generally dissatisfied with this and would welcome information on the subject. The study discusses the implications of the findings and makes recommendations to meet the needs of the teachers.     

Featherweight Java with dynamic and static overloading

We propose FMJ (Featherweight Multi Java), an extension of Featherweight Java with encapsulated multi-methods thus providing dynamic overloading. Multi-methods (collections of overloaded methods associated to the same message, whose selection takes place dynamically instead of statically as in standard overloading) are a useful and flexible mechanism which enhances re-usability and separation of responsibilities. However, many mainstream languages, such as, e.g., Java, do not provide it, resorting to only static overloading.The proposed extension is conservative and type safe: both “message-not-understood” and “message-ambiguous” are statically ruled out. Possible ambiguities are checked during type checking only on method invocation expressions, without requiring to inspect all the classes of a program. A static annotation with type information guarantees that in a well-typed program no ambiguity can arise at run-time. This annotation mechanism also permits modeling static overloading in a smooth way.Our core language can be used as the formal basis for an actual implementation of dynamic (and static) overloading in Java-like languages.     

Voxelized Minkowski sum computation on the GPU with robust culling

We present a new approach for computing the voxelized Minkowski sum (excluding any enclosed voids) of two polyhedral objects using programmable Graphics Processing Units (GPUs). We first cull out surface primitives that will not contribute to the final boundary of the Minkowski sum, analyzing and adaptively bounding the rounding errors of the culling algorithm to solve the floating point error problem. The remaining surface primitives are then rendered to depth textures along six orthogonal directions to generate an initial solid voxelization of the Minkowski sum. Finally we employ fast flood fill to find all the outside voxels. We generate both solid and surface voxelizations of Minkowski sums without enclosed voids and support high volumetric resolution of 1024³ with low video memory cost. The whole algorithm runs on the GPU and is at least one order of magnitude faster than existing boundary representation (B-rep) based algorithms. It avoids the large number of 3D Boolean operations needed in most existing algorithms and is easy to implement. The voxelized Minkowski sums can be used in a variety of applications including motion planning and penetration depth computation.     

On spiking neural P systems and partially blind counter machines

A k-output spiking neural P system (SNP) with output neurons, , generates a tuple of positive integers if, starting from the initial configuration, there is a sequence of steps such that during the computation, each O _i generates exactly two spikes aa (the times the pair aa are generated may be different for different output neurons) and the time interval between the first a and the second a is n _i . After the output neurons generate their pairs of spikes, the system eventually halts. We give characterizations of sets definable by partially blind multicounter machines in terms of k-output SNPs operating in a sequential mode. Slight variations of the models make them universal.     

A theory of mode of action of azolylalkylquinolines as DNA binding agents using automated flexible ligand docking

Azolylalkylquinolines (AAQs) are a family of quinolines with varying degrees of cytotoxic activity (comparable or moderately superior to adriamycin in some cases) developed in the past decade in our group where their exact mode of action is still unclear. In this study the most probable DNA binding mode of AAQs was investigated employing a novel flexible ligand docking approach by using AutoDock 3.0. Forty-nine AAQs with known experimental inhibitory activity were docked onto d(CGCAAATTTGCG)(2), d(CGATCG)(2) and d(CGCG)(2) oligonucleotides retrieved from the Protein Data Bank (PDB IDs: 102D, 1D12 and 1D32, respectively) as the representatives of the three plausible models of interactions between chemotherapeutic agents and DNA (groove binding, groove binding plus intercalation and bisintercalation, respectively). Good correlation (r(2)=0.64) between calculated binding energies and experimental inhibitory activities was obtained using groove binding plus intercalation model for phenyl-azolylalkylquinoline (PAAQ) series. Our findings show that the most probable mode of action of PAAQs as DNA binding agents is via intercalation of quinolinic moiety between CG base pairs with linker chain and azole moiety binding to the minor groove.